2-phenylbenzyl bromide

2-phenylbenzyl bromide - Names and Identifiers

Name	2-phenylbenzyl bromide
Synonyms	2-PHENYLBENZYL BROMIDE 2-phenylbenzyl bromide 2-(BROMOMETHYL)BIPHENYL 2-(BroMoMethyl)-1,1-biphenyl 2-(BroMoMethyl)-1,1'-biphenyl 1,1-Biphenyl, 2-(bromomethyl)- 1,1'-Biphenyl, 2-(bromomethyl)- 1-(bromomethyl)-2-phenylbenzene
CAS	19853-09-9
InChI	InChI=1/C13H11Br/c14-10-12-8-4-5-9-13(12)11-6-2-1-3-7-11/h1-9H,10H2

2-phenylbenzyl bromide - Physico-chemical Properties

Molecular Formula	C13H11Br
Molar Mass	247.13
Density	1.353 g/mL at 25 °C (lit.)
Melting Point	45-46 °C
Boling Point	120-125 °C/0.1 mmHg (lit.)
Flash Point	>230°F
Vapor Presure	1.77E-05mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	n20/D 1.6280(lit.)

2-phenylbenzyl bromide - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN 3265 8/PG 2
WGK Germany	3
Hazard Class	8
Packing Group	III

2-phenylbenzyl bromide - Upstream Downstream Industry

Raw Materials

2-BIPHENYLMETHANOL
2-Bromobenzyl bromide
METHYL BIPHENYL-2-CARBOXYLATE
2-PHENYLBENZYLAMINE HYDROCHLORIDE
2-CYANOBIPHENYL
2-Phenyltoluene
2-Biphenylcarboxaldehyde
Phenylboronic acid
2-Bromobenzyl alcohol
2-Bromobenzaldehyde
2-Bromotoluene
Bromobenzene

2-phenylbenzyl bromide - Introduction

2-phenylbenzyl bromide is an organic compound with the chemical formula C14H11Br. It is a colorless or light yellow solid substance with an aromatic taste. The following is a detailed description of the nature, use, preparation and safety information of 2-phenylbenzyl bromide:

Nature:
-Appearance: Colorless or light yellow solid
-Boiling point: About 285 ° C
-Density: about 1.33g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dichloromethane

Use:
2-phenylbenzyl bromide is commonly used as an intermediate in organic synthesis, and its main uses are as follows:
-As the raw material of antiepileptic drugs, it plays an important role in the preparation of phenytoin and other drugs.
-can be used in the synthesis of aromatic ethers, ketones and alcohols and other organic compounds.
-Can be used as an ingredient in surfactants and antibacterial agents.
-It is also used in the preparation of dyes and light stabilizers.

Method:
The preparation method of 2-phenylbenzyl bromide is mainly synthesized by benzylation. A common preparation method is to react benzyl magnesium bromide with acetophenone to produce 2-phenylbenzyl alcohol, which is then brominated to produce 2-phenylbenzyl bromide.

Safety Information:
- 2-phenylbenzyl bromide should be used to prevent contact with skin, eyes and mucous membranes to avoid irritation and injury.
-Wear appropriate personal protective equipment such as protective gloves, glasses and face masks when using.
-Avoid inhaling its vapor or dust, and operate in a well-ventilated place.
-In case of accidental contact or inhalation, rinse immediately with water and seek medical assistance.
-During storage and transportation, keep away from fire and oxidant, avoid violent oscillation and high temperature.

Last Update：2024-04-09 15:17:54